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Asthma in Children: Researchers Envision Novel Drug to Reduce the Risk of the Disease
Asthma in Children: Researchers Envision Novel Drug to Reduce the Risk of the Disease Scientists have reached a milestone in the research of childhood asthma. For the first time, they have clarified how a certain genetic defect in children initially leads to frequent infections and later to asthma. The study, published in the American Journal of Respiratory and ...
moreScientists Reveal Adipocyte's Metabolic Role and Identify Treatment Targets
moreRising Focus on 'Inceptor' as a Type 2 Diabetes Therapeutic Target
moreTherapeutic Vaccine for Chronic Hepatitis B Enters Clinical Trial
moreWhat Our Genetic Information Tells Us About Type 2 Diabetes Risk and Complications
moreCells of the Future: A Key To Reprogramming Cell Identities
moreNew Source of Stem Cells in Injury-Affected Brains of Patients
moreUnderstanding the Role of GIP in Managing Diabetes and Obesity
The increasing amount of patients with obesity and type 2 diabetes benefit greatly from the recently developed GIPR:GLP-1R co-agonists. These novel compounds lead to substantial weight loss, offering a revolutionary approach to patients worldwide. Although the hormone glucose-dependent insulinotropic polypeptide (GIP) was already shown by Helmholtz Munich scientists to decrease body weight via the brain GIP receptor, the ...
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Interpreting Large-Scale Medical Datasets: ScPoli Enables Multi-Scale Representations of Cells and Samples
The increasing amount of data recorded in medical research can only lead to scientific breakthroughs and essential therapies for patients if interpreted and analyzed correctly. Computer scientists at Helmholtz Munich developed a generative model named scPoli (single-cell population level integration), that performs ...
moreDeepMB: A Deep Learning Framework For High-Quality Optoacoustic Imaging in Real-Time
morePress Release: Exercise and Muscle Regulation: Implications for Diabetes and Obesity
How do our muscles respond at the molecular level to exercise? Researchers at Helmholtz Munich and the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) have unraveled the cellular basis and signaling pathways responsible for the p ositive impact of physical activity ...
moreTake a Deep Breath: Early Detection of Vascular Disease in Chronic Lung Disease of Premature Infants
Premature infants often struggle with breathing and require ventilatory support and oxygen therapy. Unfortunately, this might lead to lung damage resulting in lifelong consequences and chronic disease. Dr. Anne Hilgendorff’s team from Helmholtz Munich and the LMU University Hospital developed a non-invasive ...
moreA New Ally in Fighting Brain Diseases: Our Very Own Skull
moreLife Science Factory to Open a New Location in Munich in 2024
moreWildDISCO: Visualizing Whole Bodies in Unprecedented Detail
moreClimate change and heat: What is the impact on people with diabetes?
The increase in heat periods as a result of climate change can be more critical for people with diabetes than for metabolically healthy people. This is especially true at older ages. The article "Heat and diabetes" from diabinfo.de deals with helpful tips for people with diabetes ...
morePotentiating Cancer Vulnerability to Ferroptosis: Off-Targeting Effects of DHODH Inhibitors
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New Approach in Cancer Therapy With Innovative Mechanism-of-Action for Ferroptosis Induction
moreFirst Integrated Single-Cell Atlas of the Human Lung
Can a human organ be mapped on a single-cell level to learn about the functionality of each individual cell? And can we learn how different these cells are from person to person? Helmholtz Munich researchers and their collaborators have taken up this challenge and developed the Human Lung Cell Atlas using artificial intelligence (AI)-based techniques. This atlas elucidates the diversity of single lung cell types and ...
moreUnraveling the Mode of Action of Tirzepatide
Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes. Although the drug is designed to activate receptors for glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), the contribution of activating the GIP receptor in the overall efficacy of ...
moreDiagnosis of Type 1 Diabetes After SARS-CoV-2 Infection: Researchers Find Possible Correlation
During the COVID-19 pandemic, an increase in the chronic autoimmune disease type 1 diabetes was observed in children, also in Germany. Researchers at Helmholtz Munich and TU Dresden, in cooperation with the Kassenärztliche Vereinigung Bayern (KVB), have now investigated whether there is a temporal association between infection with the SARS-CoV-2 virus and the ...
moreAmbient ultrafine particles – very small and very dangerous?
A new study conducted by Helmholtz Munich researchers reveals that ultrafine particles, representing the smallest size fraction of particulate air pollution, might be more dangerous to human health than larger particles. These findings add to the growing body of evidence that it may be insufficient to focus on larger particle concentrations and gases when assessing public health risks. It was now published in the ...
moreType 1 Diabetes Awareness Campaign - K1DS ARE HEROES - started
moreType 1 diabetes: New findings on the development of the autoimmune disease in children
moreSwitching tracks: Changing the trafficking of the glucagon receptor in the liver regulates its metabolic signaling
moreLandscape of molecular contacts: How the coronavirus SARS-CoV-2 communicates with human cells
moreEfficient AI technology for MRI data analysis
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Vitamin K prevents cell death: a new function for a long-known molecule
more Gastrulation research reveals novel details about embryonic development
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