Accuray

Accuray: New Data Reinforce Benefits of TomoTherapy® Platform for Mainstream Radiation Therapy Treatment Indications

Sunnyvale, California (ots/PRNewswire) - Multiple Studies Presented at ESTRO 36 Demonstrate System Improves Tumor Control with Reduced Toxicities

Accuray Incorporated (NASDAQ: ARAY) announced today that studies continue to demonstrate the unmatched flexibility of the cutting-edge TomoTherapy® System to treat, with precision and efficiency, a wide variety of indications of all complexities. More than 50 studies were presented during poster and oral sessions at the 36th Annual European Society for Radiotherapy & Oncology (ESTRO) Meeting in Vienna, Austria, May 5 - 9, 2017.

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Study highlights include:

Breast

- A study evaluated hypofractionated intensity-modulated radiation 
  therapy (IMRT) using TomoHelical(TM) in 121 postmastectomy patients
  with implant-based immediate breast reconstruction (IBR). Results 
  demonstrated the TomoTherapy Treatment Planning System produced 
  high-quality treatment plans providing optimal coverage of both the
  chest wall and supraclavicular region and sparing of all organs at 
  risk. An additional analysis showed that the superior dosimetric 
  outcomes provided treatment benefits. The side effect profile 
  following treatment was favorable, with no patient experiencing 
  greater than grade 2 acute toxicity. Rates of toxicity remained low
  in 85 patients with a median follow-up of 14.2 months. Clinicians 
  at the European Institute of Oncology in Milan, Italy, conducted 
  these two studies. 

Lung

- A study of 68 patients with medically inoperable lung tumors found 
  that image-guided stereotactic body radiation therapy (SBRT) 
  delivered using TomoHelical provides an effective treatment option 
  with minimal toxicity. The study was conducted at three Italian 
  hospitals. 

Prostate

- A retrospective study evaluated the safety and efficacy of 
  preoperative TomoHelical in combination with chemotherapy in 
  patients with locally advanced rectal cancer (LARC). The three-year
  local control rate was 96.9% and treatment was well-tolerated. 
  Clinicians at two Swiss hospitals conducted the research, which 
  included the largest of this patient population to date.
- Toxicity and survival outcomes were reported for patients with 
  high-risk prostate cancer enrolled in a phase 1-2 study evaluating 
  hypofractionated TomoTherapy® and routine irradiation of pelvic 
  lymph nodes. Five- and seven-year biochemical relapse-free survival
  (bRFS) was 87% and 80%, respectively; cancer-specific survival was 
  98% and 96%. Treatment was well-tolerated. Clinicians at the San 
  Raffaele Scientific Institute in Milano, Italy conducted the study.
- Researchers at three European centers assessed the feasibility of 
  boosting radiation dose to the dominant intraprostatic lesion (DIL)
  using the TomoTherapy System and found it to be a viable treatment 
  option. Additionally, based on a dosimetric comparison of treatment
  plans, the system performed better than volumetric modulated arc 
  radiotherapy (VMAT) in terms of achievable boost doses, target 
  coverage and organ at risk sparing, and was similar in several 
  aspects to intensity-modulated proton therapy (IMPT).   

"The data presented at the ESTRO 36 meeting continue to show that the benefits of the TomoTherapy® System's ring gantry platform and daily 3D image guidance in the treatment of a range of clinical indications." said Fabienne Hirigoyenberry, VP Global Medical and Scientific Affairs of Accuray. "The Radixact(TM) System, the latest generation TomoTherapy platform, provides the same unrivaled delivery capabilities while giving clinicians the versatility to treat the broad spectrum of patients and disease types with the highest level of precision and increased speed and efficiency."

About Accuray

Accuray Incorporated (NASDAQ: ARAY) is a radiation oncology company that develops, manufactures, and sells precise, innovative tumor treatment solutions that set the standard of care with the aim of helping patients live longer, better lives. The company's leading-edge technologies deliver the full range of radiation therapy and radiosurgery treatments. For more information, please visit www.accuray.com" class="uri-ext outbound" rel="nofollow">http://www.accuray.com.http://www.accuray.com.

Safe Harbor Statement

Statements made in this press release that are not statements of historical fact are forward-looking statements and are subject to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements in this press release relate, but are not limited, to clinical applications, clinical results, patient outcomes and Accuray's leadership position in radiation oncology innovation and technologies. Forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from expectations, including but not limited to the risks detailed from time to time under the heading "Risk Factors" in the company's report on Form 10-K, filed on August 24, 2016, the company's reports on Form 10-Q, filed on November 1, 2016, February 3, 2017, and May 5, 2017, and as updated periodically with the company's other filings with the SEC.

Forward-looking statements speak only as of the date the statements are made and are based on information available to Accuray at the time those statements are made and/or management's good faith belief as of that time with respect to future events. The company assumes no obligation to update forward-looking statements to reflect actual performance or results, changes in assumptions or changes in other factors affecting forward-looking information, except to the extent required by applicable securities laws. Accordingly, investors should not put undue reliance on any forward-looking statements.

Contact:

Sancie Nakarat
Accuray
Tel: +33-6-81-36-84-34
E-Mail: snakarat@accuray.com

or Liliana Silva Fernandes
Elan Edelman
Tel: +33-1-86-21-50-37
E-Mail: liliana.silvafernandes@elanedelman.com

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